UJI AKTIVITAS DAN KARAKTERISASI NANOEMULSI EKSTRAK AKAR GOBO SEBAGAI ANTISARIAWAN TERHADAP Streptococcus mutans

Authors

  • Muhtar Mohammad Wildan Program Studi Sarjana Farmasi, Fakultas Farmasi, Universitas Bakti Tunas Husada Tasikmalaya Jawa Barat, Indonesia
  • Nurdianti Lusi Program Studi Sarjana Farmasi, Fakultas Farmasi, Universitas Bakti Tunas Husada Tasikmalaya Jawa Barat, Indonesia
  • Yuliana Anna Program Studi Sarjana Farmasi, Fakultas Farmasi, Universitas Bakti Tunas Husada Tasikmalaya Jawa Barat, Indonesia

DOI:

https://doi.org/10.36423/pharmacoscript.v9i2.2111

Keywords:

Akar Gobo, Nanoemulsi, Antibakteri

Abstract

Akar Gobo sebagai pangan dan bahan obat bagi masyarakat Asia salah satunya Indonesia yang mengandung metabolit sekunder dapat bersifat antibakteri. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri spray nanoemulsi ekstrak akar gobo terhadap pertumbuhan streptococcus mutans dengan metode sumuran. Nanoemulsi yang dihasilkan memiliki karakteristik yang baik, dengan ukuran globul berkisar antara 20,69 hingga 21,73 nm. Nilai indeks polidispersitas (PDI) berada pada rentang 0,16–0,28, menunjukkan distribusi ukuran partikel yang relatif seragam. Selain itu, zeta potensial nanoemulsi berada pada kisaran (-15,9) hingga (-7,21) mV, mengindikasikan stabilitas sistem yang cukup baik akibat adanya tolakan elektrostatik antarglobul. Ekstrak akar gobo memiliki aktivitas anti bakteri dalam pengujian bentuk ekstrak dan nanoemulsi. Hasil penelitian menunjukkan bahwa ekstrak nanoemulsi memiliki aktivitas antibakteri dengan zona 5,03 mm ± 1,12 kategori sedang.

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Published

2026-10-19

Issue

Vol. 9 No. 2 (2026): Pharmacoscript

Section

Articles

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Copyright (c) 2026 Muhtar Mohammad Wildan, Nurdianti Lusi, Yuliana Anna

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